Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic ImpairmentChinese Full Text
YUE Ai-xia;The Yishui Central Hospital in Linyi City of Shandong Province Department of Rehabilitation medicine;
Abstract: Objective: The purpose is to observe curative effect of Xingshen Tongluo needle medicin improve ischemic stroke at recovery phase on neurologic impairment and its influence on cerebral blood flow speed and vascular endothelial function. Method: Eighty-four cases patients were randomly divided into control group（42 cases） and observation group（42 cases） according to digital method. Both groups were received secondary prevention plan ischemic brain death conventional cure in secondary prevention plan,including anti-platelet aggregation,blood sugar control,blood pressure control,regulating blood lipids et. Observation group took Xingshen Tongluo decoction on the basis of therapy in control group,1 does/day,conventional water frying. At the same time adopt Xingshen Tongluo acupuncture,3 times/week. Treatment courses for the two groups continued 8 weeks. Before the treatment,give a mark of nervous functional defects degree with stroke patient and record activities of daily living（ADL）. Measuring arteria cerebri anterior（ACA） through transcranial doppler instrument’s treatment,middle cerebral artery（MCA）,posterior cerebral artery（PCA） and basilar artery（BA） blood flow rate in cerebral infarction side. Detect the level of nitric oxide（NO） and endothelins1（ET-1）. Result: The total effective rate of disease curative effect in the observation group was 83. 33% superior to 57. 14% of the control group（P ＜ 0. 05）. After treatment,except consciousness factor,in the observation group,the score of the degree of neural function defect score standard（CSS） and the total score of CSS were lower than those in the control group（P ＜ 0. 01）. And the score of ADL was higher than that of the control group（P ＜ 0. 01）,after treatment,patients’ illness in both group were improved. Besides blood velocity of ACA and MCA in observation group were better than those in the control group（P ＜ 0. 01）. For the two groups,compared with the time before treatment,blood velocity of PCA both improved（P ＜ 0. 01）. After treatment the level of NO in the two groups both increased,observation group which higher than that of the control group（P ＜ 0. 01）. And endothelins1（ET-1） in the two groups both decreased,and for the observation group which lower than that of the control group（P ＜ 0. 01）. Conclusion: For ischemic type stroke patients,it can improve blood velocity of ACA and MCA Xingshen Tongluo needle medicine with drug was used in convalescence,and it improved function of vascular endothelium,cerebral blood perfusion,Promote the recovery of neural function.
Keywords：
ischemic stroke; Xingshen Tongluo decoction; Xingshen Tongluo acupuncture; vascular endothelial function; haemodynamics;
- DOI：
10.13422/j.cnki.syfjx.2014100200
- Series：
- Subject：
- Classification Code：
R743.3
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